Issue 22, 2009
From the journal:

Organic & Biomolecular Chemistry

Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates†

Catherine F. Carter,a   Ian R. Baxendale,a   Matthew O'Brien,a   John B. J. Paveyb  and  Steven V. Ley*a  

* Corresponding authors

a Department of Chemistry, Innovative Technology Centre, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: svl1000@cam.ac.uk

b AstraZeneca, Bakewell Road, Loughborough, Leics, UK

Abstract

The syntheses of butane-2,3-diacetal protected tartrate derivatives are described using continuous flow processing techniques with in-line purification and I.R. analytical protocols.

Graphical abstract: Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates

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Article information

DOI
https://doi.org/10.1039/B917289K
Article type
Communication
Submitted
21 Aug 2009
Accepted
04 Sep 2009
First published
28 Sep 2009

Org. Biomol. Chem., 2009,7, 4594-4597

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Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates

C. F. Carter, I. R. Baxendale, M. O'Brien, J. B. J. Pavey and S. V. Ley, Org. Biomol. Chem., 2009, 7, 4594 DOI: 10.1039/B917289K

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