Issue 4, 2010
From the journal:

Chemical Communications

SERS aptasensor from nanorod–nanoparticle junction for protein detection†

Yuling Wang,a   Kyuwan Leea  and  Joseph Irudayaraj*a  

* Corresponding authors

a Physiological Sensing Facility, Bindley Biosciences Center and Birck Nanotechnology Center, Purdue University 225 S. University Street, 215 ABE Building, West Lafayette, USA
E-mail: josephi@purdue.edu
Fax: 765-49-40388

Abstract

A multicomponent nanostructure comprising of gold nanorod–nanoparticle (AuNR–AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod–nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.

Graphical abstract: SERS aptasensor from nanorod–nanoparticle junction for protein detection

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Article information

DOI
https://doi.org/10.1039/B919607B
Article type
Communication
Submitted
21 Sep 2009
Accepted
04 Nov 2009
First published
18 Nov 2009

Chem. Commun., 2010,46, 613-615

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SERS aptasensor from nanorod–nanoparticle junction for protein detection

Y. Wang, K. Lee and J. Irudayaraj, Chem. Commun., 2010, 46, 613 DOI: 10.1039/B919607B

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