Issue 8, 2010
From the journal:

Natural Product Reports

On the potential of natural products in the discovery of pharma leads: A case for reassessment†

Samuel Danishefsky*a  

* Corresponding authors

a Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA; Columbia University, 3000 Broadway, New York, NY 10027, USA

Abstract

The central proposition advanced herein is that complex target oriented synthesis, enabled by historic advances in methodology, has enormously expanded the scope of the possible. Accordingly, natural products, a proven long-term source of pharma discovery, re-emerge as potentially valuable elements for synthesis-driven pharma exploitation.

Graphical abstract: On the potential of natural products in the discovery of pharma leads: A case for reassessment

  • This article is part of the themed collection: Synthesis
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Article information

DOI
https://doi.org/10.1039/C003211P
Article type
Viewpoint
Submitted
15 Feb 2010
First published
09 Apr 2010

Nat. Prod. Rep., 2010,27, 1114-1116

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On the potential of natural products in the discovery of pharma leads: A case for reassessment

S. Danishefsky, Nat. Prod. Rep., 2010, 27, 1114 DOI: 10.1039/C003211P

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