The sponge Agelas oroides contains 4,5-di-bromopyrrole-2-carboxylic acid (4), the corresponding nitrile and amide; oroidin contains an amide derived from (4) and a substituted 2-aminoimidazole.
S. Forenza, L. Minale, R. Riccio and E. Fattorusso, J. Chem. Soc. D, 1971, 1129 DOI: 10.1039/C29710001129
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