Issue 14, 2012
From the journal:

RSC Advances

Well-controlled synthesis of boronic-acid functionalised poly(lactide)s: a versatile platform for biocompatible polymer conjugates and sensors†

Alison J. Cross,a   Matthew G. Davidson,*a   Daniel García-Vivóa  and  Tony D. James*a  

* Corresponding authors

a Centre for Sustainable Chemical Technologies, Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
E-mail: m.g.davidson@bath.ac.uk, t.d.james@bath.ac.uk

Abstract

We report the controlled synthesis of boronic-acid terminated polylactides via the use of a protected boronic acid-functionalised ring-opening polymerisation initiator and the subsequent deprotection of the resultant polymer. We have demonstrated the utility of this approach to biocompatible polymer conjugates of biologically-relevant diols using an indicator-displacement assay.

Graphical abstract: Well-controlled synthesis of boronic-acid functionalised poly(lactide)s: a versatile platform for biocompatible polymer conjugates and sensors

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Article information

DOI
https://doi.org/10.1039/C2RA20373A
Article type
Communication
Submitted
29 Feb 2012
Accepted
03 May 2012
First published
04 May 2012

RSC Adv., 2012,2, 5954-5956

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Well-controlled synthesis of boronic-acid functionalised poly(lactide)s: a versatile platform for biocompatible polymer conjugates and sensors

A. J. Cross, M. G. Davidson, D. García-Vivó and T. D. James, RSC Adv., 2012, 2, 5954 DOI: 10.1039/C2RA20373A

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