Download MendeleyCrystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs
Pallan, P.S., Yang, X., Sierant, M., Abeydeera, N.D., Hassell, T., Martinez, C., Janicka, M., Nawrot, B., Egli, M.To be published.
4RC0
X-ray structure of RNA containing guanosine phosphorodithioate
- PDB DOI: https://doi.org/10.2210/pdb4RC0/pdb
- NAKB: 4RC0
- Classification: RNA
- Organism(s): synthetic construct
- Mutation(s): No
- Deposited: 2014-09-13 Released: 2015-09-16
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.13 Å
- R-Value Free: 0.211
- R-Value Work: 0.181
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar nucleic acids by: Sequence | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | Organism | Image | |
| 5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*(A2M)P*(2SG)P*CP*G)-3' | 12 | synthetic construct |  | ||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.13 Å
- R-Value Free: 0.211
- R-Value Work: 0.181
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 40.914 | α = 90 |
| b = 34.836 | β = 127.5 |
| c = 32.274 | γ = 90 |
| Software Name | Purpose |
|---|---|
| MD2 | data collection |
| MOLREP | phasing |
| SHELXL-97 | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2015-09-16 Deposition Author(s): Pallan, P.S., Egli, M.
Revision History (Full details and data files)
- Version 1.0: 2015-09-16
Type: Initial release - Version 1.1: 2017-07-12
Changes: Refinement description - Version 1.2: 2023-09-20
Changes: Data collection, Database references, Derived calculations, Refinement description
