4WO3

THE SECOND C-KIT DNA QUADRUPLEX CRYSTAL STRUCTURE

  • Classification: DNA
  • Organism(s): Homo sapiens
  • Mutation(s): No 

  • Deposited: 2014-10-15 Released: 2014-10-29 
  • Deposition Author(s): Wei, D., Neidle, S.
  • Funding Organization(s): Cancer Research UK

Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.73 Å
  • R-Value Free: 0.243 
  • R-Value Work: 0.182 
  • R-Value Observed: 0.185 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history. 


Literature

THE SECOND C-KIT1 DNA QUADRUPLEX CRYSTAL STRUCTURE

Wei, D., Neidle, S.

To be published.

Macromolecules

Find similar nucleic acids by:  Sequence   |   3D Structure  

Entity ID: 1
MoleculeChains LengthOrganismImage
DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3')A [auth B],
B [auth A]		22Homo sapiens
Sequence Annotations
Expand
  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.73 Å
  • R-Value Free: 0.243 
  • R-Value Work: 0.182 
  • R-Value Observed: 0.185 
  • Space Group: H 3
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 94.85α = 90
b = 94.85β = 90
c = 30.363γ = 120
Software Package:
Software NamePurpose
REFMACrefinement
SCALAdata scaling
PHASESphasing
XIAdata reduction

Structure Validation

View Full Validation Report



View more in-depth experimental data
Entry History & Funding Information

Deposition Data

Funding OrganizationLocationGrant Number
Cancer Research UKUnited KingdomC129/A4489
Cancer Research UKUnited Kingdoma China Fellowship

Revision History  (Full details and data files)

  • Version 1.0: 2014-10-29
    Type: Initial release
  • Version 1.1: 2014-11-26
    Changes: Derived calculations, Non-polymer description, Other, Refinement description, Structure summary
  • Version 1.2: 2019-06-12
    Changes: Data collection, Database references
  • Version 1.3: 2024-01-10
    Changes: Data collection, Database references, Derived calculations, Refinement description