Download MendeleyCrystal Structure of Putative NAD(P)H-Flavin Oxidoreductase from Neisseria meningitidis
Kim, Y., Maltseva, N., Endres, M., Crofts, T., Joachimiak, A.To be published.
6WT2
Crystal Structure of Putative NAD(P)H-Flavin Oxidoreductase from Neisseria meningitidis
- PDB DOI: https://doi.org/10.2210/pdb6WT2/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Neisseria meningitidis Z2491
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2020-05-01 Released: 2020-05-13
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.75 Å
- R-Value Free: 0.218
- R-Value Work: 0.193
- R-Value Observed: 0.194
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Putative NAD(P)H-flavin oxidoreductase | 224 | Neisseria meningitidis Z2491 | Mutation(s): 0 Gene Names: NMA1015 |  | |
UniProt | |||||
Find proteins for A0A0U1RIB4 (Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)) Explore A0A0U1RIB4 Go to UniProtKB: A0A0U1RIB4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A0U1RIB4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 5 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| FMN (Subject of Investigation/LOI) Query on FMN | G [auth A], K [auth B], O [auth C], S [auth D] | FLAVIN MONONUCLEOTIDE C17 H21 N4 O9 P FVTCRASFADXXNN-SCRDCRAPSA-N |  | ||
| NIO Query on NIO | E [auth A], H [auth B], L [auth C], Q [auth D] | NICOTINIC ACID C6 H5 N O2 PVNIIMVLHYAWGP-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | I [auth B], M [auth C] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| FMT Query on FMT | P [auth D] | FORMIC ACID C H2 O2 BDAGIHXWWSANSR-UHFFFAOYSA-N |  | ||
| CL Query on CL | F [auth A], J [auth B], N [auth C], R [auth D] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B, C, D | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.75 Å
- R-Value Free: 0.218
- R-Value Work: 0.193
- R-Value Observed: 0.194
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 81.556 | α = 90 |
| b = 70.167 | β = 89.961 |
| c = 85.624 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
| HKL-3000 | phasing |
| MOLREP | phasing |
| Coot | model building |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-05-13 Deposition Author(s): Kim, Y., Maltseva, N., Endres, M., Crofts, T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | -- |
Revision History (Full details and data files)
- Version 1.0: 2020-05-13
Type: Initial release - Version 1.1: 2023-10-18
Changes: Data collection, Database references, Refinement description - Version 1.2: 2023-11-15
Changes: Data collection
