A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection

Cunhao Fan; Jingjie Lai; Xilong Zhou; Yuanhao Liu; Zhiying Shao; Kezuo Di; Fuheng You; Lijun Ding; Kun Wang

doi:10.1039/D4CC01174K

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A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection†

Cunhao Fan,^a Jingjie Lai,^a Xilong Zhou,^a Yuanhao Liu,^a Zhiying Shao,^b Kezuo Di,^a Fuheng You,^a Lijun Ding^b and Kun Wang

*^a

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* Corresponding authors

^a School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, PR China
E-mail: wangkun@ujs.edu.cn

^b Key Laboratory for Theory and Technology of Intelligent Agricultural Machinery and Equipment, Jiangsu University, Zhenjiang 212013, PR China

Abstract

A study of an integrated OPECT biosensor gate and the EC color-changing region on the same chip was carried out, achieving sensitive detection through bioetching-induced signal changes. Enzymatic bioetching enables specific alkaline phosphatase (ALP) detection by catalyzing the production of CdS, which modulates the channel current and generates a visual signal.

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DOI: https://doi.org/10.1039/D4CC01174K
Article type: Communication
Submitted: 13 Mar 2024
Accepted: 25 Mar 2024
First published: 05 Apr 2024

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Chem. Commun., 2024,60, 4581-4584

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A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection

C. Fan, J. Lai, X. Zhou, Y. Liu, Z. Shao, K. Di, F. You, L. Ding and K. Wang, Chem. Commun., 2024, 60, 4581 DOI: 10.1039/D4CC01174K

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Chemical Communications

A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection†

Abstract

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A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection

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