Fe3+-mediated selective 1,2-Se (S) bifunctionalization of olefin

Abstract

A one-pot, four-component reaction for simultaneously constructing C–Se, C–S, and C–N bonds via iron-mediated olefin 1,2-bifunctionalization was described. β-Selenylethyl dithiocarbamates were obtained highly efficiently with a wide substrate scope and remarkable regioselectivity. Notably, non-activated olefins exhibit higher reactivity in this reaction system, achieving yields of up to 99%.